Onir naltrexone prescription bottle on a sunlit kitchen counter, daily medication to reduce alcohol cravings

The world's first
GLP-1 for alcohol.

One pill a day that scientifically quiets the noise of alcohol, so putting the bottle down, or not picking it up at all becomes easier. 

90% success rate · 1,200+ clinical studies · 80% of users lose weight

23,871+
PRESCRIPTIONS FILLED
4.9/5
REVIEWS
Onir naltrexone prescription bottle on a marble kitchen counter, daily medication to curb alcohol cravings

The world's first
GLP-1 for alcohol.

One pill a day that scientifically quiets the noise of alcohol, so putting the bottle down, or not picking it up at all becomes easier. 

90% success rate · 1,200+ clinical studies · 80% of users lose weight

23,871+
PRESCRIPTIONS FILLED
4.9/5
REVIEWS
Built around your goals, not a label
Prescribed by licensed U.S. physicians
Available in all 50 states
Discreet, private, judgment-free
WHAT DRINKING QUIETLY COSTS

The cost of drinking is rarely the drinking itself.

It's the morning that starts slow. The 2pm slump. The workout that didn't happen. The conversation you didn't quite have. For some people, it's a glass of wine that became three. For others, it's the knowledge that something has to change, and not knowing where to start.

WHY PEOPLE CHOOSE ONIR

5 reasons people use Onir to drink less.

01
It's biology, not willpower

Alcohol works on the brain's reward system. Naltrexone works on the same system, blocking the receptors that make drinking feel rewarding. When the reward quiets, so does the craving.

02
You don't have to quit

No labels, no all-or-nothing rules. Onir is built around your goal, whether that's drinking less, stopping for a while, or stopping for good.

03
You get real things back

Better sleep. Clearer mornings. Steadier energy and focus. Members talk less about what they gave up and more about what came back.

04
Nobody needs to know

No meetings, no insurance claims, no pharmacy small talk. A private online assessment and discreet, unmarked delivery to your door.

05
The math makes sense

Most members were spending more on alcohol every month than the entire program costs. Cutting back tends to pay for itself.

WATCH, 2 MINUTES

A clinician explains how it actually works.

No hype, no jargon. Just a clear explanation of what naltrexone does in the brain, why one daily pill changes your relationship with alcohol, and what the first few weeks tend to feel like.

Captions included. Watch with sound on or off.

Friends sharing a clear-headed morning around the breakfast table, life after reducing alcohol with Onir
A QUIETER RELATIONSHIP WITH ALCOHOL

Mornings that feel like yours again.

YOU'VE SEEN THIS STORY BEFORE

GLP-1s quiet the food noise. Onir quiets the alcohol noise.

Millions of people know the feeling GLP-1 medications create around food: the constant mental chatter just gets quieter. Onir uses naltrexone, an FDA-approved medication in clinical use since 1994, to do something remarkably similar for alcohol.

MEMBER STORY

When the alcohol noise quiets, life opens back up.

One daily pill. No meetings. No labels. Just a private, clinician-prescribed way to change your relationship with alcohol.

WHEN ALCOHOL TAKES UP TOO MUCH SPACE

It's not always a crisis. Sometimes it's just more than you want.

Maybe it's the extra glass you didn't plan on. The slower morning. The promise to "take it easy" that keeps getting pushed. Whatever your goal, Onir helps you approach it with medical support instead of willpower alone.

The automatic pour

"When the decision starts to feel made before you make it."

The slow morning

"When sleep, energy, and focus don't feel like they should."

The repeat promise

"When you keep telling yourself you'll reset next week."

The mental load

"When alcohol takes up more attention than you want it to."

THE SCIENCE, AS COVERED IN
  • Mayo Clinic
  • The New York Times
  • PBS News
  • Business Insider
  • Cleveland Clinic
GET BACK WHAT DRINKING TAKES

The returns, in real numbers.

79%
Sleep better
Deeper, more restorative sleep within weeks.
69%
Perform better at work
Sharper focus, more consistent energy.
46%
Lose weight
Without a diet. Just less liquid calories.
100+
Clear mornings a year
Back in your life, not lost to a hangover.
$3,100
Saved per year
The average member saves more than the program costs.

Self-reported. Individual results vary.

Most members notice the first shift in about two weeks. The real change, the one that feels permanent, tends to arrive around 90 days in.

That's why Onir is designed as a 90-day program.

BUILT AROUND YOUR GOALS

What does control look like for you?

There is no single "right" goal. Onir is designed around the change you want to make.

Your clinician reviews your goals and health history to determine whether Onir is appropriate.

HOW ONIR WORKS

Three steps. No video calls.

1
60 SECONDS

Take the quiz

Tell us about your drinking, your goals, and your health. Our clinicians will review and determine if Onir is right for you.

2
Within 24 hours

Clinician review

No video calls. No intake interview. A licensed medical provider reviews your assessment within 24 hours and either prescribes Onir or, if it isn't the right fit, tells you why and what might help instead.

3
Discreet delivery

Medication to your door

Discreet, unmarked packaging. Ongoing clinical support and a health coach who meets you where you are, whether that's drinking less or stopping completely. Cancel anytime.

Onir 90-day welcome kit, prescription naltrexone bottle, clinician welcome card, progress journal, and weekly pill case
WHAT ARRIVES

Delivered discreetly to your door.

A 90-day supply of your medication arrives in plain, unmarked packaging, nothing visible to anyone but you. Inside, a note from your clinician with what to expect in your first weeks and how to reach them when you need to.

  • Your clinician stays on call by message, 7 days a week
  • Discreet, unmarked shipping, no branding, no insurance paperwork
  • Refills auto-ship every 90 days. Pause or cancel anytime.
Close-up of a single Onir naltrexone tablet on marble, FDA-approved medication for alcohol use disorder
THE SCIENCE

It's not willpower. It's brain chemistry.

When you drink, your brain releases a wave of endorphins that reinforces the behavior. That's why drinking often feels automatic, your brain has learned to want it.

Naltrexone, the active ingredient in Onir, gently blocks the receptors that carry that reinforcement. The drink still goes down. It just doesn't light up the same pathway. Over time, the pull weakens, and cravings lose their grip. The choice stays yours, whether that means drinking less or not at all.

  • FDA-approved for AUD treatment for 30+ years
  • Non-addictive, non-habit-forming
  • Prescribed by licensed U.S. physicians
  • Safe for long-term use
IS ONIR RIGHT FOR YOU?

Built for people who want alcohol to take up less space.

GOOD FIT

Onir may be right if…

  • You want to drink less, stop, or feel more in control
  • You want a private medical option
  • You don't want meetings or public labels
  • You want support without judgment
  • You want a plan built around your own goals
NOT THE RIGHT FIT

Onir isn't for…

  • You currently use opioids
  • You need emergency care or detox support
  • You are looking for crisis treatment
  • Your clinician determines the medication isn't appropriate

Real clinicians. Real credentials.

Onir is backed by a team of U.S.-licensed physicians and clinicians specializing in alcohol use.

Portrait of Sam Mitchell, a U.S.-licensed clinician specializing in alcohol use

Hi, I'm Sam

I've spent years focused on moderation-led approaches, sustainable behavior change, and the science of cravings.

"I help people understand what's actually happening in the brain when drinking feels automatic, and what we can do about it. Most people aren't trying to quit. They're trying to drink less. Onir was built for both."

MEMBER STORIES

Real mornings, back.

Jenna, 43, an Onir member who cut nightly wine drinking, sitting outdoors with a mug in afternoon light

"I didn't want to quit. I just wanted the nightly bottle of wine to stop feeling automatic. It took about ten days."

, Jenna, 43

WORKING ON NIGHTLY WINE

Marcus, 38, an Onir member reducing weekend drinking, checking his fitness watch in the morning

"My Whoop recovery score went from 38% average to 71% in two months. I thought I was just a bad sleeper. Turns out I was a drinker."

, Marcus, 38

CUTTING WEEKEND DRINKING

Alex, 47, an Onir member who stopped drinking alcohol, standing in a home kitchen with a mug by the window

"I was scared it would feel like a loss. It feels like the opposite. I'm more present than I've been in ten years."

, Alex, 47

CHOSE TO STOP COMPLETELY

FROM REAL MEMBERS

Rated Excellent on Trustpilot

Trustpilot
4.8 out of 5

Michael Burchell

US · 1 review

August 17, 2026

New user. Very pleased

I started using my meditation about 8 days ago. I feel amazing. Dont really have any urges to drink alcohol. Went to dinner last weekend and ordered a glass of wine. Did not even finish it.

Joseph Barba

US · 1 review

Aug 12, 2026

Appreciate the simplicity of the process

Really good experience so far…. simple process, quick delivery, responsive and helpful team.

Will Miller

US · 1 review

Jul 29, 2026

Empowered not ashamed

As someone who travels constantly for work and whose line of work frequently involves happy hours and events where alcohol is present, I wasn't sure how well this would fit into my life. That said, Onir has turned out to be one of the best health decisions I've made all year....

Elliott Orkin

US · 1 review

Jul 28, 2026

Great Experience

Before signing up I did one of their free consultations and ended up talking to one of the co-founders, Quinten. He answered all of my questions without feeling like he was trying to sell me. If you are on the fence, i'd recommend reaching out to their team to chat it through!

Arowland

US · 1 review

August 19, 2026

Onboard process smooth

With some many products on the market I was skeptical but after some research and completing their onboarding process it was a super easy process and The Dr's were very thorough and professional.

Jeffrey McDaniel

US · 1 review

July 24, 2026

Down from 4-5 beers a night to less than 2 — and it's only been a week

I've tried to cut back on drinking before, but willpower alone never stuck. I started this medication a week ago mostly out of curiosity, not expecting much this fast....

HOW WE COMPARE

Why people choose Onir instead of going it alone.

Onir
Apps & trackers
Going it alone
Built around your goal
Yes
Sometimes
Depends
Medical support
Licensed clinician review
No
No
Targets cravings
Prescription may reduce reinforcement
Tracking only
Willpower only
Private
Yes
Varies
Yes
No meetings required
Yes
Varies
Yes
Supports drinking less or stopping
Yes
Varies
Depends
PRIVACY & DISCRETION

Private by design.

No insurance required

We don't bill insurance, so there's no insurance claim.

Discreet packaging

Medication ships in unmarked packaging.

No video calls required

Complete your assessment privately, online.

Judgment-free care

Your goals are yours. Your care team is here to support them.

WHAT IT COSTS

Less than $3.30 a day.

Onir is $99/ month for a 90-day program, your medication, clinician care, and ongoing support included.

That's less than a coffee a day. Most members save more than the program costs in the first six months just from drinking less.

Cancel anytime. No insurance required. No hidden fees.

FREQUENTLY ASKED

The questions we hear most.

No. Naltrexone, the active ingredient in Onir, is non-addictive and non-habit-forming. It has been FDA-approved for treating alcohol use disorder for over 30 years.

Onir is $99/ month for a 90-day program, your medication, clinician care, and ongoing support included. That's less than $3.30 a day. No insurance required, cancel anytime.

Only if you want it to. Onir doesn't bill through insurance, so there's no insurance record. We won't contact your primary care doctor unless you ask us to, though we recommend keeping your full care team informed when you're ready.

Most members notice a shift in 10–14 days. If it isn't right for you, your clinician will adjust your plan or you can cancel anytime.

No. Onir supports however you want to change your relationship with alcohol, whether that's drinking less on weeknights, taking a longer break, or stopping completely. Your clinician will build your plan around your goals, not ours.

Most medications are fine, but naltrexone is not compatible with opioids. Your clinician will review your full medication history before prescribing.

Most members notice the pull weakening within 10–14 days, and many see improvements in sleep and energy in the first month.

Yes. Your assessment is seen only by your licensed clinician. We never sell your data, never share with insurance, and never contact your employer or primary care doctor unless you ask us to.

The next version of your mornings starts here.

It takes 60 seconds. Your answers are private. A medical provider will review and reach out.

Onir is not a substitute for emergency care, detox, or crisis support. If you are in crisis or need immediate medical help, call 911 or 988. Prescription medication is provided only if a licensed clinician determines it is appropriate. Results vary.